Melford E. Spiro, 1920–2014

Melford: Using Neural Networks to Find Spreadsheet Errors

Spreadsheets are widely used for financial and other types of important numerical computations. Spreadsheet errors have accounted for hundreds of millions of dollars of financial losses, but tools for finding errors in spreadsheets are still quite primitive. At the same time, deep learning techniques have led to great advances in complex tasks such as speech and image recognition. In this paper...

Dum Spiro, Spero

It is my sad editorial duty to acknowledge that Professor David Hadden, previous editor of this Journal died earlier this year. As a previous editor he has his obituary published here and I thank Professor Patrick Bell for rising to this sad task so diligently. David bore his final illness with great dignity, clearly determined that while he was alive, he would live (dum vivimus, vivamus). The ...

Spiro Table of Contents

Spiro Table of Contents

T H E Ultrastructure of Striated Muscle at Various Sarcomere Lengths*. by David Spiro, M.d,

I t is generally believed that muscular contractility involves a reversible interaction of the two proteins, actin and myosin. The manner in which this interaction produces contraction or relaxation is not clear, but the fact that it is extremely difficult to demonstrate a change in the wide angle x-ray diffraction pattern when muscle shortens (2) suggests that contractility is associated with ...